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Since 90% of the bodys serotonin originates in the gut, modulating enteric serotonin production could influence central serotonergic tone through vagal afferents that relay gut signals to brain serotonin-producing raphe nuclei

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Frye et al., However, just because metabolic abnormalities are associated with a disorder such as ASD, it does not mean that they are causative or that even correcting them may have an effect

Patients who wear contact lenses can use saline drops to moisten the eyes or switch to glasses during treatment to reduce irritation